Functional
PMMA
microparticles
with a very narrow size distribution
were synthesized by photoinitiated RAFT dispersion in aqueous ethanol using an
acrylic acid oligo copolymer as a macro-RAFT agent.
Accurate
control of particle size at relatively narrow polydispersity remains key
challenge in the production of synthetic polymer particles at scale. A
cross-flow membrane emulsification technique was utilized here in the
preparation of Poly
(Methyl Methacrylate) Microsphere
to demonstrate its application for such a manufacturing challenge.
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| Poly(Methyl Methacrylate) Microspheres |
Applications of PMMA microparticles
The
range of uses for polymeric microspheres continues to cultivate across a wide
scope of technology areas. In numerous cases, particles with inhibited size
characteristics are required. For uses such as particle sizing standards this
is self-evident, but it has also long been a requirement for chromatography
applications where the particles act as the absorbent stationary phase as well
as variations in surface area affects the retention.
Over
the last few decades, polymer microspheres have found escalating use in
biomedical applications. The integration of pharmaceutical actives inert
carrier particles is frequently described as a route for novel drug delivery
materials; as well as the link between drug availability and particle size is
now well established, offering further impetus for managing particles sizes
precisely.
Passage into and
through the body is also known to be dependent on particle size, for instance
inhaler applications have a very tight particle size requirement. Finally, we
conclude that there is an ever-growing interest in micro-particles for use in
medical imaging uses, where again good size control is a key prerequisite. If
you are in search of high-quality PMMA microparticles for your research needs,
consider buying from Alpha Nanotech.
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