Polystyrene nanoparticles
of various shapes, sizes, as well as materials carrying diverse surface
modification have numerous technological and biomedical applications. Yet the
mechanism by which nano particles interact with biological structures and their
biological impact and hazards remain poorly investigated.
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| Polystyrene Nanoparticles |
Due
to their large surface to volume ratio, Polystyrene nanospheres or particles usually exhibit properties
that vary from those of bulk materials. Particularly, the surface chemistry of
the nanoparticles is very important for their sturdiness as well as solubility
in biological media as well as for their bio-compatibility and
bio-distribution. Polystyrene does not mortify in the cellular environment and
displays no short-term cytotoxicity.
As
polystyrene nanoparticles easily synthesised in an extensive range of sizes
with discrete surface functions. They perfectly suited as model particles to
study the effects of the particle surface features on diverse biological
parameters.
Action of Polystyrene nano particles
Nano-sized
polystyrene materials are promising tools for new technologies in industrial,
pharmaceutical as well as medical applications. On the other hand,
nanoparticles may cause difficult cellular events ranging from acute
cytotoxicity, induction of inflammation to genetoxic effects. Even if acute
different cellular effects are not as obvious as, for example cell death and
inhibition of proliferation, biopersistance and accumulation of NPs may interfere with the physiological
function of cells as well as organs.
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